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IKBKB — SPP1
Text-mined interactions from Literome
Das et al., J Biol Chem 2003
(Breast Neoplasms) :
However, both pharmacological ( wortmannin and LY294002 ) and genetic ( Deltap85 ) inhibitors of PI 3'-kinase inhibited
OPN induced Akt phosphorylation,
IKK activity, and NFkappaB activation through phosphorylation and degradation of IkappaBalpha
Rice et al., J Vasc Res 2006
:
Finally, functional inhibition of integrin beta3 dependent NF-kappaB signaling decreases
OPN induced IkappaBalpha,
IKKbeta and NIK phosphorylation
Fong et al., Lung Cancer 2009
(Adenocarcinoma...) :
Stimulation of A549 cells with
OPN also
induced IkappaB kinase alpha/beta ( IKK alpha/beta ) phosphorylation, IkappaBalpha phosphorylation, p65 Ser ( 536 ) phosphorylation, and kappaB-luciferase activity