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PTX4 — VEGFA

Text-mined interactions from Literome

Zhou et al., Acta Pharmacol Sin 2009 (Disease Models, Animal...) : In this study, we investigated the effect of PTX on tubulointerstitial fibrosis and the expression of vascular endothelial growth factor ( VEGF ) in a rat model of obstructive nephropathy
Szajnik et al., Oncogene 2009 (Carcinoma...) : In MyD88 ( + ) SCOV3 cells, LPS or PTX binding to TLR4 induced IRAK4 activation and cJun phosphorylation, activated the NF-kappaB pathway and promoted interleukin (IL)-8, IL-6, vascular endothelial growth factor and monocyte chemotactic protein-1 production and resistance to drug induced apoptosis
Tang et al., Neuroreport 2013 (Disease Models, Animal...) : However, the effect of PTx on VEGF has never been studied ... Primary neurons were cultured to assess the direct effect of PTx on neuronal VEGF expression ... Our findings suggest that upregulation of endogenous neuronal VEGF by PTx protects motor deficits in EAE and it is a potential therapeutic option for multiple sclerosis
Amirkhosravi et al., Thromb Haemost 1998 (Neoplasm Metastasis...) : Pentoxifylline ( PTX ) , a methylxanthine derivative, significantly inhibited the hypoxia induced increase in PCA as well as VEGF release in all three cell lines tested