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HIF1A — IL8
Text-mined interactions from Literome
Colla et al., Blood 2007
(Multiple Myeloma...) :
In turn, we show that the inhibition of
HIF-1alpha by siRNA
suppressed IL-8 and OPN production by MM cells under hypoxia
Cane et al., Cell Microbiol 2010
:
HIF-1alpha mediates the induction of
IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour ... Using RNA interference we show that bacteria induced
HIF-1alpha regulates the expression of
IL-8 , VEGF and Twist1, thereby pointing to a role for HIF-1 in angiogenesis and inflammation