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MECP2 — MYLIP

Text-mined interactions from Literome

Klein et al., Nat Neurosci 2007 : Block of miR132 mediated repression increased MeCP2 and brain derived neurotrophic factor (BDNF) levels in cultured rat neurons and the loss of MeCP2 reduced BDNF and miR132 levels in vivo
Nomura et al., Hum Mol Genet 2008 (Fragile X Syndrome...) : MeCP2 dependent repression of an imprinted miR-184 released by depolarization ... The restricted release of MeCP2 from the paternal allele results in paternal allele-specific expression of miR-184
Wada et al., Int J Cancer 2010 (Intestinal Neoplasms...) : miR-212 is downregulated and suppresses methyl-CpG binding protein MeCP2 in human gastric cancer ... Ectopic expression of miR-212 repressed expression of the MeCP2 protein but not the MECP2 mRNA level
Szulwach et al., J Cell Biol 2010 : MeCP2 mediated epigenetic regulation of one such miRNA, miR-137 , involves coregulation by Sox2, a core transcription factor in stem cells
Lu et al., Exp Cell Res 2013 (Down Syndrome) : The expression levels of miR-155 and miR-802 in T21 AF-iPS-NPCs were highly elevated in the presence of low expression of MeCP2
Ji et al., Carcinogenesis 2013 (Cell Transformation, Neoplastic) : Moreover, inhibition of miR-152 expression in 16HBE cells could increase DNMT1 expression and result in an increase in DNA methylation, DNMT1 and MeCP2 binding to miR-152 promoter, indicating an interaction between miR-152 and DNMT1 is regulated by a double negative circuit
Han et al., Genes Dev 2013 : Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p ... Here, we show that miR-483-5p , an intragenic microRNA of the imprinted IGF2, regulates MeCP2 levels through a human-specific binding site in the MECP2 long 3 ' UTR ... These data provide insight into the role of miR-483-5p in regulating the levels of MeCP2 and interacting proteins during human fetal development