Gene interactions and pathways from curated databases and text-mining

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MCOLN1 — RAD51

Text-mined interactions from Literome

Kenne et al., Mutat Res 1987 (Anemia, Aplastic...) : The RecA-like activity, dependent on ATP and Mg2+ , was detected at an elevated level only in the human and rodent cell lines, GM1492 and CHO respectively
Namsaraev et al., J Biol Chem 1998 : Rad51p binding to both 1-N6-ethenoadenosine and 3-N4-ethenocytidine ssDNA ( epsilonDNA ) and dsDNA requires the presence of Mg2+ and ATP ; no binding occurs in the presence of ADP, AMP-PNP, or ATPgammaS
Namsaraev et al., Biochemistry 1998 : Interaction of Rad51 with ATP and Mg2+ induces a conformational change in Rad51
Zaitseva et al., J Biol Chem 1999 : Rad51 protein binds both single stranded DNA ( ssDNA ) and double stranded DNA ( dsDNA ) in an ATP- and Mg2+ dependent manner, over a wide range of pH, with an apparent binding stoichiometry of approximately 1 protein monomer per 4 ( +/-1 ) nucleotides or base pairs, respectively