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Han et al., Mol Cell Neurosci 2008
:
Among them, insulin and insulin-like growth factor (IGF) family are found to promote the neuronal differentiation of NPCs. Akt activation has been indicated to be responsible for the
insulin/IGF-I induced
neuronal differentiation ... In this study, we have demonstrated that mTOR is involved in the
insulin induced
neuronal differentiation
Xu et al., Biochem J 1995
:
Ethanol either abolished or severely muted the short- and long-term insulin mediated upregulation of NTP expression, and substantially reduced
insulin mediated
neuronal differentiation
Dikic et al., Curr Biol 1994
:
PC12 cells overexpressing the insulin receptor undergo
insulin dependent
neuronal differentiation