Gene interactions and pathways from curated databases and text-mining

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LEP — REG1A

Text-mined interactions from Literome

Kushner et al., Diabetes 2004 (Diabetes Mellitus, Type 1) : Protein tyrosine phosphatase-1b (Ptp1b) inhibits insulin and leptin signaling by dephosphorylating specific tyrosine residues in their activated receptor complexes
Benomar et al., Endocrinology 2009 : Interestingly, leptin as well as insulin induced the expression of phosphotyrosine phosphatase (PTP)-1B , whereas CNTF treatment did not affect its expression
Walduck et al., Frontiers in immunology 2012 : Here we discuss the hypothesis that vaccination deregulates T ( reg ) responses in the gastric mucosa, and that this process is mediated by leptin