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APOB — SCARB1

Pathways - manually collected, often from reviews:

• Reactome Reaction: APOB → SCARB1 (reaction) Rhainds et al., Eur J Biochem 1999*, Li et al., J Biol Chem 2002*, Bultel-Brienne et al., J Biol Chem 2002*, Vishnyakova et al., J Biol Chem 2003*, Baranova et al., J Biol Chem 2005*, Murao et al., J Biol Chem 1997*, Xu et al., J Lipid Res 1997*, Calvo et al., Arterioscler Thromb Vasc Biol 1997*
• Reactome Reaction: APOB → SCARB1 (indirect_complex) Rhainds et al., Eur J Biochem 1999*, Li et al., J Biol Chem 2002*, Bultel-Brienne et al., J Biol Chem 2002*, Vishnyakova et al., J Biol Chem 2003*, Eckhardt et al., J Biol Chem 2004*, Baranova et al., J Biol Chem 2005*, Nieland et al., Biochim Biophys Acta 2005*, Eckhardt et al., J Biol Chem 2006*, Pagler et al., J Biol Chem 2006*, Zhang et al., Mol Membr Biol 2007*, Sun et al., J Lipid Res 2007*, Babitt et al., J Biol Chem 1997*, Murao et al., J Biol Chem 1997*, Xu et al., J Lipid Res 1997*, Calvo et al., Arterioscler Thromb Vasc Biol 1997*

Text-mined interactions from Literome

Rhainds et al., J Cell Sci 2004 : SR-BI dependent LDL- and HDL-CE selective uptake are affected differently by the integrity of membrane rafts, but both occur by a retroendocytic pathway in HepG2 cells
Lam et al., Atherosclerosis 2004 : Glycoxidized LDL was able to significantly induce SR-A and CD36 expression by 3- and 4.5-fold, respectively, in macrophages whereas SR-BI expression was suppressed by glycoxidized LDL , glycated LDL and oxidized LDL
Bourret et al., Int J Biochem Cell Biol 2006 : In vivo cholesteryl ester selective uptake of mildly and standardly oxidized LDL occurs by both parenchymal and nonparenchymal mouse hepatic cells but SR-BI is only responsible for standardly oxidized LDL selective uptake by nonparenchymal cells
Yu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 : Low levels of ox-LDL may enhance the LXRalpha-ABCA1-apoA-I pathway in adipocytes, up-regulate SR-BI mRNA expression, and then increase the cholesterol efflux
Hayashi et al., Am J Physiol Gastrointest Liver Physiol 2011 (Dyslipidemias...) : SR-B1 overexpression in Caco-2 cells increased apolipoprotein B (apoB) 100 and apoB48 secretion, whereas RNAi knock down of SR-B1 decreased secretion of both apoB100 and apoB48