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CPB1 — IL10

Text-mined interactions from Literome

Naldini et al., Cytokine 1999 : To understand further the cytokine mediated regulation of the complex physiological and immunological changes induced by CPB, the authors decided to investigate whether CPB affects the release of interleukin (IL)-10 , as well as other cytokines, in correlation to the inhibition of T cell responses ... In all patients, CPB significantly enhances IL-10 and IL-6 production in resting and PHA stimulated PBMC
Dehoux et al., Crit Care Med 2000 : Our results demonstrate the following : a ) CPB induces an early and transient LPS hyporesponsiveness of whole blood as measured by cytokine production ; b ) IL-10 seems only partly involved in this process, and its role is restricted to an in vivo situation ; and c ) contact of blood with an ECC is sufficient to induce LPS hyporesponsiveness
Reis Miranda et al., Eur J Cardiothorac Surg 2005 (Postoperative Complications...) : CPB caused a significant increase of IL-6, IL-8, and IL-10 in all groups