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CD86 — IL10

Text-mined interactions from Literome

Liu et al., Scand J Immunol 1999 (Lupus Erythematosus, Systemic) : The effects of interleukin-10 (IL-10) on the expression of CD80 and CD86 on monocytes from patients with SLE and normal controls were similar ... IL-10 down-regulated the expression of CD86 while it slightly enhanced that of CD80
Blazevic et al., J Clin Immunol 2001 : Inhibition studies using the B7-binding fusion protein CTLA4Ig and antibodies against CD80 and CD86 demonstrate that CTLA4Ig and anti-CD86 inhibited influenza-specific T cell proliferation, interleukin (IL)-2 and interferon (IFN)-gamma production, and generation of influenza-specific CD8+ CTL
Gray et al., Blood 2002 : These studies indicated that H-ferritin induced relatively greater expression of CD86 and B7-H1 on MoDCs and that monoclonal antibodies against their receptors, CTLA-4 and programmed death receptor-1 (PD-1), inhibited IL-10 production from the regulatory T cells
Janssen et al., Am J Respir Cell Mol Biol 2002 (Asthma...) : This IL-10 production by the OVA-Mphi was dependent on MHC-TCR and CD86-CD28 , but not CD80-CD28 or CD40-CD154 interactions
Salek-Ardakani et al., Virology 2002 : Viral IL-10 in a concentration dependent manner inhibited both basal- and IFN-gamma induced HLA-class II, ICAM-1 ( basal levels of ICAM-2 and ICAM-3 is unaffected ), CD80, and CD86 up-regulation when added simultaneously with IFN-gamma
Mainali et al., Cell Immunol 2004 : However, Dx added during pre-DCs differentiation into immature DCs, prompted GcR translocation to the nucleus, enhanced DC apoptosis, suppressed differentiation to CD1a+ cells, inhibited expression of CD86 , reduced subsequent CD83 expression, maintained DC endocytic activity, suppressed IL-6 secretion, enhanced IL-10 secretion, and reduced DC-mediated T cell stimulation
Steers et al., Vaccine 2008 : L ( LA ) enhanced the surface expression of MHC class I, class II, CD80, and CD86 molecules, induced the secretion of IFN-gamma, IL-12p40, TNF-alpha and IL-10 , and caused a shift in the proteasome profile from constitutive to immunoproteasomes as observed by the induction of beta2i, beta5i, PA28alpha, and PA28beta subunits
Kim et al., J Immunol 2009 : CD28 mediated costimulation dramatically enhanced T cell IL-10 production, yet neither ICOS nor CD86 was involved in IL-10 production
Wang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 (Melanoma, Experimental) : In the DCs with down-regulated SOCS1 expression, the expressions of MHCII and CD86 increased a little, which did not differ significantly from the control DCs, and IL-10 level dropped and IL-12p40 went up significantly compared with the control DCs
Ozawa et al., Eur J Immunol 1996 : Based on the recently reported effect of interferon (IFN)-gamma and interleukin (IL-)-10 on the expression of CD80 and CD86 by LC, we examined the effects of these cytokines on the expression of CD54 ( intercellular adhesion molecule-1 ) and CD40 in addition to CD80 and CD86 on LC, and correlated the expression of each co-stimulatory molecule with antigen presentation for a Th1 clone by cultured LC (cLC) treated with these cytokines
Zhang et al., Cell Immunol 1997 : Both CD80 and CD86 were able to provide costimulation for interferon-gamma and IL-2 synthesis by rhesus CD4+ T cells, but CD80 costimulation also resulted in synthesis of IL-4 and IL-10
Furuie et al., Eur Respir J 1997 (Pulmonary Fibrosis) : The inhibitory effect of interleukin (IL)-10 on the accessory cell function of AMs and the expression of CD80 and CD86 on AMs were also investigated