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Gregorc et al., Biol Chem 2005
:
These data suggest that caspase mediated cleavage of hDLG , and other MAGUKs, and their removal from sites of cell-cell contacts is an early step in the disruption of adherens junctions and dismantling of cell-cell contacts during apoptosis
Friedrichs et al., J Mol Med (Berl) 2008
(Crohn Disease...) :
Thus, DLG5 likely acts in the regulation of NFkB activation or caspase activation as part of host defence mechanisms