◀ Back to EPHB2

AREG — EPHB2

Text-mined interactions from Literome

Göoz et al., J Biol Chem 2006 : ERK phosphorylation was attenuated by 1 ) neutralizing EGFR antibodies and the EGFR kinase inhibitor, AG1478, 2 ) neutralizing HB-EGF, but not amphiregulin , antibodies, heparin, or CM197, and 3 ) pharmacological inhibitors of matrix degrading metalloproteinases or TACE small interfering RNA
Wayne et al., Mol Endocrinol 2007 : Lastly, the EGF-like factor amphiregulin (AREG) activated RAS and ERK1/2 phosphorylation in granulosa cells by mechanisms that were selectively blocked by an EGFR antagonist but not by an SFK antagonist
Noma et al., Mol Endocrinol 2011 : Collectively, these results document that the expression of type III NRG1 is induced in granulosa cells during ovulation and that NRG1 enhances AREG induced ERK1/2 phosphorylation in both granulosa cells and cumulus cells