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FOXO3 — TNF
Text-mined interactions from Literome
Abid et al., J Biol Chem 2005
(Hyperplasia) :
PDGF-BB,
tumor necrosis factor-alpha , and insulin-like growth factor 1 treatment
resulted in the nuclear exclusion of
FoxO , whereas PDGF-BB alone down-regulated the FoxO target gene, p27 ( kip1 ), and enhanced cell survival and progression through the cell cycle
Moylan et al., Am J Physiol Cell Physiol 2008
:
We used TNF treated C2C12 myotubes to test the hypothesis that
AKT-Foxo1/3 signaling
mediates TNF regulation of atrogin mRNA
Dejean et al., Nat Immunol 2009
(Arenaviridae Infections) :
Stimulation of dendritic cells mediated by the coinhibitory molecule CTLA-4
induced nuclear localization of
Foxo3 , which in turn inhibited the production of interleukin 6 and
tumor necrosis factor
Snoeks et al., Lab Invest 2009
(Colitis...) :
TNFalpha induces the translocation of nuclear
FOXO3 into the cytosol where it undergoes proteasomal degradation in human intestinal HT-29 cells
Sheriff et al., Mol Cell Endocrinol 2012
(Burns...) :
DAG also reversed or attenuated the
TNF+IFN induced reduction in phosphorylation of Akt,
FOXO1 , 4E-BP-1, and GSK-3ß in myotubes
Lin et al., J Endod 2013
:
We assessed
tumor necrosis factor (TNF)-a stimulated expression of Cyr61 and phosphorylated inactive
FoxO3a ( p-FoxO3a ) in MC3T3-E1 murine osteoblasts by Western analysis
Tang et al., Zhonghua Xin Xue Guan Bing Za Zhi 2013
:
TNF-a also significantly
activated the phosphorylation of PTEN, AKT and
FOXO3a ( P < 0.05 )