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CCR7 — IL12B
Text-mined interactions from Literome
Yang et al., J Clin Immunol 2001
:
However, when purified T cells instead of unfractionated PBL were stimulated with anti-CD3/CD28 and then exposed to IL-12 or IFN-alpha,
CCR5 expression was
induced by
IL-12 but not by IFN-alpha
Wan et al., Blood 2004
:
The induction of interferon-gamma-inducible protein 10 ( IP-10 ) secretion by Hsp70L1 is not shared by Hsp70, and other functional differences include more potent stimulation of DC
IL-12p70 , CC-chemokine, and
CCR7 and CXCR4 expression by Hsp70L1. Immunization of mice with the hybrid peptide Hsp70L1-ovalbumin ( OVA ) ( 257-264 )
induces an OVA ( 257-264 ) -specific Th1 response and cytotoxic T lymphocyte ( CTL ) that results in significant inhibition of E.G7-OVA tumor growth
Penna et al., J Immunol 2007
:
1,25 ( OH ) ( 2 ) D ( 3 ) also decreased
IL-12p75 production by M-DCs, as expected, and
inhibited CCR7 expression
Dauer et al., J Immunol Methods 2008
:
These `` conventional '' FastDC are mature, migrate in
response to
CCR7 ligation and effectively stimulate autologeous T cells in vitro, but are deficient in
IL-12p70 production
Ni et al., Br J Pharmacol 2009
(Encephalomyelitis, Autoimmune, Experimental) :
In addition, TAK-779 did not affect production of
IL-12 by antigen presenting cells,
CCR5 induction on T cells and the potential of MOG-specific T cells to transfer EAE