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Risbud et al., Spine (Phila Pa 1976) 2004 (MAP Kinase Signaling System) : Pharmacological inhibition of ERK1/2 and p38 enzymatic activity resulted in a decrease in Sox-9, aggrecan , and collagen type II mRNA levels
Risbud et al., Spine (Phila Pa 1976) 2006 (MAP Kinase Signaling System) : Moreover, inhibition of ERK activity, in the presence TGF-beta3, resulted in suppression of collagen Type II, aggrecan , TGF-beta-RI, TGF-beta-RII and TGF-beta-RIII mRNA expression