Gene interactions and pathways from curated databases and text-mining

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IL4 — UMOD

Text-mined interactions from Literome

Yang et al., J Biol Chem 2002 : These data provide a mechanism whereby IL-4 may indirectly affect Thp function via PPARgamma activated by macrophage products of the 12/15-LO pathway
Khan et al., J Biol Chem 2012 : CD4+ T cell derived novel peptide Thp5 induces interleukin-4 production in CD4+ T cells to direct T helper 2 cell differentiation ... Here, we show that Thp5 , a novel peptide with structural similarity to vasoactive intestinal peptide, regulates production of early IL-4 in newly activated CD4 ( + ) T cells ... Induction of IL-4 in CD4 ( + ) T cells by Thp5 is independent of the transcription factor STAT6 but dependent on ERK1/2 signaling