Gene interactions and pathways from curated databases and text-mining

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ARSA — IL2

Text-mined interactions from Literome

Cianferoni et al., Blood 2001 : In contrast, ASA did not affect IL-13, interferon-gamma, and IL-2 expression ... ASA inhibited IL-4, but not IL-2 , promoter-driven chloramphenicol acetyltransferase expression in transiently transfected Jurkat T cells
Brzozowski et al., J Pharmacol Exp Ther 2004 (Stomach Diseases) : The area of ASA induced gastric lesions, gastric blood flow ( GBF ), expression of mRNA and protein of leptin and plasma leptin, gastrin, interleukin-1beta , and tumor necrosis factor-alpha levels were examined
Hernandez et al., Hum Immunol 2007 : Both BAY- and ASA-allogeneic DC and autologous alloantigen pulsed DC were weaker stimulators of T cells ( by MLR ) compared with controls, and there was reduced IL-2 and IFN-gamma production by T cells stimulated with BAY-DC or ASA-DC ( by ELISPOT ) ( more marked results were always observed with ASA treated DC )
Fujiwara et al., Jpn J Pharmacol 1990 : Neither SP nor 5-ASA inhibited the IL-2 production
Stevens et al., J Pharmacol Exp Ther 1995 : 5-ASA ( 625 microM ) markedly reduced culture supernatant IL-2 protein levels by 92 % and steady-state IL-2 messenger RNA levels 4.4-fold at 24 and 18 hr, respectively