Mallampalli et al., J Biol Chem 2000
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Tumor necrosis factor-alpha inhibits expression of CTP : phosphocholine cytidylyltransferase ... TNFalpha reduced the activity of CTP : phosphocholine cytidylyltransferase ( CCT ), the rate-regulatory enzyme within the CDP-choline pathway, by 40 % compared with control, but it did not alter activities of choline kinase or cholinephosphotransferase
Awasthi et al., Am J Physiol Lung Cell Mol Physiol 2001
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Am J Physiol Lung Cell Mol Physiol 281 : L98-L107, 2001 ), we demonstrated that tumor necrosis factor (TNF)-alpha inhibited the activity of CTP : phosphocholine cytidylyltransferase ( CT ), the rate limiting enzyme in the de novo synthesis of phosphatidylcholine ( PC ), and that its actions were likely exerted through a metabolite of sphingomyelin