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MMP12 — MMP7
Text-mined interactions from Literome
Tan et al., Am J Respir Cell Mol Biol 2006
(Pneumonia...) :
No increases in RNA levels of MMP-2,
MMP-9 , or MMP-8 were found, but levels of MMP-7,
MMP-12 , and MMP-13 RNA did
increase at 14 d ... No increases in RNA levels of MMP-2,
MMP-9 , or MMP-8 were found, but levels of
MMP-7 , MMP-12, and MMP-13 RNA did
increase at 14 d
Dozier et al., Med Chem 2006
:
Whether the additional collagenases,
MMP-8 and MMP-13, are also
activated by
MMP-7 has not been explored
Madala et al., J Immunol 2010
(Fibrosis...) :
Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like
MMP12 ,
MMP13 expression was highly
dependent on IL-13 and type II-IL-4 receptor signaling
Yuan et al., Zhongguo Gu Shang 2012
(Osteoarthritis, Knee) :
Western blotting showed that beta-catenin, MMP-7 expression in OA synoviocytes was significantly higher than normal group, Bushen Huoxue decoction could significantly reduce beta-catenin,
MMP-7 expression ; ELISA results showed that MMP-7 expression of OA synovial supernatant was significantly higher than normal synoviocytes supernatant, Bushen Huoxue decoction significantly
regulated the level
MMP-7 down
Li et al., PloS one 2012
(Disease Models, Animal...) :
Similar results were observed in the study using
MMP408 , a pharmacological
inhibitor of
MMP-12