Gene interactions and pathways from curated databases and text-mining

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MMP12 — MMP7

Text-mined interactions from Literome

Tan et al., Am J Respir Cell Mol Biol 2006 (Pneumonia...) : No increases in RNA levels of MMP-2, MMP-9 , or MMP-8 were found, but levels of MMP-7, MMP-12 , and MMP-13 RNA did increase at 14 d ... No increases in RNA levels of MMP-2, MMP-9 , or MMP-8 were found, but levels of MMP-7 , MMP-12, and MMP-13 RNA did increase at 14 d
Dozier et al., Med Chem 2006 : Whether the additional collagenases, MMP-8 and MMP-13, are also activated by MMP-7 has not been explored
Madala et al., J Immunol 2010 (Fibrosis...) : Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like MMP12 , MMP13 expression was highly dependent on IL-13 and type II-IL-4 receptor signaling
Yuan et al., Zhongguo Gu Shang 2012 (Osteoarthritis, Knee) : Western blotting showed that beta-catenin, MMP-7 expression in OA synoviocytes was significantly higher than normal group, Bushen Huoxue decoction could significantly reduce beta-catenin, MMP-7 expression ; ELISA results showed that MMP-7 expression of OA synovial supernatant was significantly higher than normal synoviocytes supernatant, Bushen Huoxue decoction significantly regulated the level MMP-7 down
Li et al., PloS one 2012 (Disease Models, Animal...) : Similar results were observed in the study using MMP408 , a pharmacological inhibitor of MMP-12