Gensch et al., J Biol Chem 2004
:
Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK
Song et al., Gastroenterology 2005
(Colonic Neoplasms) :
Electrophoretic mobility shift assays, site directed mutagenesis, and chromatin immunoprecipitation were used to monitor the participation of AP-1 in MUC2 transcription ... Mutation in the AP-1 site markedly decreased MUC2 promoter activity, and MUC2 transcription was inhibited by cotransfection with a dominant negative AP-1 vector
Lim et al., American journal of translational research 2009
:
Ras-Raf1-ERK1/2 dependent AP-1 activation positively regulates MUC5AC mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it