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NOS2 — PTPN4

Text-mined interactions from Literome

Szabó et al., Crit Care Med 1999 (Disease Models, Animal...) : Here we examined the effect of mercaptoethylguanidine (MEG) , an inducible nitric oxide synthase inhibitor and peroxynitrite scavenger, in a severe hemorrhagic shock model
Wolfárd et al., Shock 2000 (Endotoxemia...) : We determined the effects of the inducible nitric oxide synthase inhibitor and free radical scavenger mercaptoethylguanidine (MEG) on the myocardial contractility, the endothelial and inducible nitric oxide synthase ( eNOS and iNOS ) activities, and the activation and tissue accumulation of polymorphonuclear leukocytes in hyperdynamic endotoxemia in dogs ... MEG selectively inhibits iNOS in vivo, but its beneficial effects are rather related to the decreases in leukocyte and free radical mediated myocardial dysfunction during early endotoxemia
Soejima et al., Shock 2000 (Pulmonary Edema...) : The animals were then randomised into two groups : MEG group [ 30 mg/kg mercaptoethylguanidine (MEG) , selective inhibitor of iNOS and peroxynitrite scavenger, was given 1 h after injury and then 8 h for 41 h, n = 7 ] and control group ( 0.9 % NaCl, n = 7 )
Soejima et al., Am J Respir Crit Care Med 2001 (Burns...) : To test the hypothesis, we administered mercaptoethylguanidine (MEG) , a selective iNOS inhibitor , to conscious sheep subjected to a combined smoke inhalation and third-degree burn injury to 40 % of total body surface area
Soejima et al., Burns Incl Therm Inj 2001 (Burns...) : The animals were divided into two groups : a MEG group [ iNOS was inhibited with mercaptoethylguanidine (MEG) , a selective inhibitor of iNOS , n=6 ] and a control group ( n=6 )
Daghigh et al., J Periodontol 2002 : Addition of mercaptoethyl guanidine (MEG) , a specific inhibitor of iNOS , profoundly reduced the production of NO in HGF
Moochhala et al., J Trauma 2005 (Brain Injuries) : We studied the effects of mercaptoethylguanidine (MEG) , a dual inhibitor of the inducible iNOS and COX with scavenging effect on peroxynitrite, on physiologic variables, brain pathogenesis, and neurologic performance in rats after a lateral fluid percussive induced TBI
Lohinai et al., Br J Pharmacol 1998 (Disease Models, Animal...) : In the present study, using mercaptoethylguanidine (MEG) , a selective inhibitor of iNOS and a peroxynitrite scavenger, we investigated the role of iNOS and peroxynitrite in a rat model of periodontitis
Zingarelli et al., J Pharmacol Exp Ther 1998 (Body Weight...) : The effect of mercaptoethylguanidine (MEG) , a selective inhibitor of the inducible nitric oxide synthase and peroxynitrite scavenger, was evaluated in a rat model of colonic injury ... MEG also reduced the appearance of iNOS and nitrotyrosine immunoreactivity in the colon