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ADAM17 — MYLIP

Text-mined interactions from Literome

Reddi et al., Genes & cancer 2011 : Up-regulation of miR-122 negatively regulates ADAM-17 , a known downstream target, in thyroid cells, suggesting an antiangiogenic mechanism in thyroid carcinoma
Xu et al., Exp Cell Res 2012 (Colorectal Neoplasms) : We found that elevated levels of miR-222 in the mimics transfected HCT116/L-OHP and HCT-8/VCR cells reduced the ADAM-17 protein level and the luciferase activity of an ADAM-17 3 ' untranslated region based reporter and sensitized these cells ' apoptosis to some anticancer drugs
Doberstein et al., Neoplasia (New York, N.Y.) 2013 (Carcinoma, Renal Cell) : In the present work, we provide evidence using overexpression and inhibition of microRNA 145 (miR-145) that miR-145 negatively regulates ADAM17 expression ... Furthermore, we show that ADAM17 negatively regulates miR-145 through tumor necrosis factor-a, resulting in a reciprocal negative feedback loop