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ARAF — PIK3R1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ARAF — PIK3R1 (direct interaction, pull down) Fang et al., Biochem Biophys Res Commun 2002*
• IRef Hprd Interaction: ARAF — PIK3R1 (in vivo) King et al., J Biol Chem 2000*, Fang et al., Biochem Biophys Res Commun 2002*
• IRef Hprd Interaction: ARAF — PIK3R1 (in vitro) King et al., J Biol Chem 2000*, Fang et al., Biochem Biophys Res Commun 2002*
• IRef Intact Interaction: ARAF — PIK3R1 (direct interaction, pull down) King et al., J Biol Chem 2000*
• IRef Intact Interaction: ARAF — PIK3R1 (physical association, coimmunoprecipitation) King et al., J Biol Chem 2000*
• IRef Intact Interaction: ARAF — PIK3R1 (direct interaction, phage display) King et al., J Biol Chem 2000*
• IRef Ophid Interaction: ARAF — PIK3R1 (aggregation, confirmational text mining) King et al., J Biol Chem 2000*
• IRef Ophid Interaction: ARAF — PIK3R1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Sutor et al., J Biol Chem 1999 : Moreover, A-Raf activation , like MEK activation, was blocked by inhibition of PI3-K but was insensitive to cAMP
Mahon et al., Cell Signal 2005 : Thus, A-Raf can regulate PLCgamma1 signalling via a PDGFR dependent mechanism and may also regulate PI3K signalling via a PDGFR independent mechanism