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COMT — CYP19A1

Text-mined interactions from Literome

Fu et al., Breast Cancer Res Treat 2010 (Breast Neoplasms...) : In MCF7 cells, TSA treatment suppressed ERalpha, CYP1B1, STS, COMT , SULT1A1, and SULT2B1 but induced ERbeta, CYP19 and SULT2A1 mRNA expression
Salama et al., PloS one 2009 (Leiomyoma...) : In addition, COMT over expression or treatment with 2ME reduced the expression of hypoxia-inducible factor -1alpha ( HIF-1 alpha ) and the basal level as well as TNF-alpha induced aromatase ( CYP19 ) expression ... COMT over expression or treatment with 2ME stabilize microtubules, ameliorates E ( 2 ) -induced proliferation, inhibits ERalpha and PR signaling, and reduces HIF-1 alpha and CYP19 expression in human uterine leiomyoma cells