Gene interactions and pathways from curated databases and text-mining

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HRH1 — IL8

Text-mined interactions from Literome

Matsubara et al., Int Arch Allergy Immunol 2006 : Histamine H1 receptor stimulated interleukin 8 and granulocyte macrophage colony stimulating factor production by bronchial epithelial cells requires extracellular signal regulated kinase signaling via protein kinase C
Minami et al., J Dent Res 2007 (MAP Kinase Signaling System...) : These results indicate that histamine induces IL-8 production from gingival fibroblasts through H1R , and synergistically augments the inflammatory stimuli by amplification of the MAPK and NF-kappaB through H1R linked PLC