◀ Back to MYLIP

FBXW7 — MYLIP

Text-mined interactions from Literome

Xu et al., J Biol Chem 2010 : We found that overexpression of miR-223 , in particular, significantly reduces FBXW7 mRNA levels, increases endogenous cyclin E protein and activity levels, and increases genomic instability
Kurashige et al., Br J Cancer 2012 (Carcinoma, Squamous Cell...) : The aim of this study was to clarify the clinical significance of miR-223 and FBXW7 in oesophageal squamous cell carcinoma ( ESCC ) patients, and to elucidate the mechanism by which FBXW7 is regulated by miR-223 ... We also investigated the role of miR-223 in the regulation of FBXW7 expression in ESCC cell lines in an in vitro analysis
Mansour et al., J Exp Med 2013 (Precursor T-Cell Lymphoblastic Leukemia-Lymphoma) : Overexpression of miR-223 also leads to marked down-regulation of FBXW7 protein expression, whereas knockdown of TAL1 leads to up-regulation of FBXW7 protein levels, with a marked reduction of its substrates MYC, MYB, NOTCH1, and CYCLIN E