Gene interactions and pathways from curated databases and text-mining

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HAS3 — TNF

Text-mined interactions from Literome

Oguchi et al., Connect Tissue Res 2004 (Arthritis, Rheumatoid...) : Differential stimulation of three forms of hyaluronan synthase by TGF-beta, IL-1beta, and TNF-alpha
Campo et al., Mol Cell Biochem 2006 : TNF-alpha , IFN-gamma, and IL-1beta modulate hyaluronan synthase expression in human skin fibroblasts : synergistic effect by concomital treatment with FeSO4 plus ascorbate
Kessler et al., Clinical and translational science 2008 (Colitis...) : We determined that human intestinal endothelial cells generate HA in response to proinflammatory stimuli by demonstrating a TNF-alpha induced increase in hyaluronan synthase-3 mRNA expression and the accumulation of HA cable-like structures that are adhesive for leukocytes