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BCL10 — FGF2

Text-mined interactions from Literome

Bryckaert et al., Oncogene 1999 : FGF2 also increased the de novo synthesis and the production of Bcl-xl before the onset of apoptosis ... Both inhibition of ERK2 activation, which decreased Bcl-xl synthesis, and downregulation of Bcl-x by antisense oligonucleotide treatment inhibited the survival promoting activity of FGF2
Cuevas et al., Neurol Res 2000 (Carotid Artery Injuries) : In addition, FGF-1 treatment also induces expression of the bcl-X anti-apoptotic protein in the same site of the media showing VSMC apoptosis
Désiré et al., J Neurochem 2000 : Exogenous FGF2 supported neuronal survival after serum deprivation and increased neuronal bcl-x ( L ) and bcl-2 expression, through binding to its receptor R1 ( FGF-R1 ), and subsequent extracellular signal regulated kinase ( ERK ) activation ... Indeed, long-term ERK activation and high bcl-x ( L ) levels are necessary for the survival activity of both exogenous and endogenous FGF2
Mascarelli et al., J Soc Biol 2001 (MAP Kinase Signaling System...) : FGF2 induces long-term activation of FGFR1 and ERK1/2, and production of the anti-apoptotic protein BcL-x
Pardo et al., J Biol Chem 2002 : Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK dependent pathway : correlation with resistance to etoposide induced apoptosis
Kim et al., BMB Rep 2012 : Chemical inhibition of FGFR, NFkB, and PI3K activity by PD173074, pyrrolidine dithiocarbamate, and LY294002 respectively abrogated the FGF-2 mediated induction of Bcl2-A1 and Bcl-xL expression