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CCNA2 — CCNB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM RC complex during G2/M-phase of cell cycle: RC complex during G2/M-phase of cell cycle complex (CCNA2-CCNB1-CDK1-PARP1-POLA1-POLD1-POLE-RFC1-RFC2-RPA1-RPA2-RPA3-TOP1) Frouin et al., EMBO J 2002
• IRef Corum Interaction: Complex of 40 proteins (association, anti bait coimmunoprecipitation) Frouin et al., EMBO J 2002
• IRef Intact Interaction: Complex of 17 proteins (association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of PKMYT1-CKS2-CCNB2-CKS1B-CCNA2-CDK1-CCNB1-CDKN1B-CDKN1A (association, tandem affinity purification) Varjosalo et al., Cell reports 2013
• IRef Intact Interaction: Complex of 18 proteins (association, tandem affinity purification) Varjosalo et al., Cell reports 2013
• IRef Intact Interaction: Complex of 27 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013
• IRef Intact Interaction: Complex of 30 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013
• IRef Intact Interaction: CCNB1 — CCNA2 (physical association, proximity ligation assay) Liu et al., Mol Cell Proteomics 2013
• STRING interaction: CCNA2 — CCNB1 (interaction, mapped from grid mint intact)
• STRING interaction: CCNB1 — CCNA2 (interaction, mapped from grid mint intact)

Text-mined interactions from Literome

Ko et al., Exp Cell Res 2004 (Adenocarcinoma...) : Hyperoxia induces significant expression of cyclin A/B1 and translocation of cyclin A into nuclei while marginally decreasing cyclin A/B1-Cdks kinase activities, which may be related to nuclear association with p21
Gong et al., Curr Biol 2007 : Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin B1
Gong et al., Mol Biol Cell 2010 : Cyclin A2 is required for the activation and nuclear accumulation of cyclin B1-Cdk1 , raising the possibility that cyclin B1-Cdk1 mediates the effects of cyclin A2