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CASP1 — NOS3
Text-mined interactions from Literome
Matsumoto et al., Shock 2003
(Necrosis) :
Both CS and TC can ameliorate hypoxia induced apoptosis in HAEC through
inhibiting caspase-3 activation by enhancing
ecNOS activity, via the accumulation of BK
Nakagawa et al., J Cell Biochem 2005
:
TNF-alpha induced decrease in the number of wild-type cells was significantly prevented by culture with caspase-3 inhibitor ( 10 ( -8 ) M ), while LPS- or Bay K 8644 induced decrease in cell number was significantly prevented by
caspase-3 inhibitor or N omega-nitro-L-arginine methylester ( NAME ) ( 10 ( -5 ) M ), an
inhibitor of
nitric oxide ( NO ) synthase
Gupta et al., J Am Soc Nephrol 2007
(Acute Kidney Injury...) :
Treatment of septic animals with APC reduced blood urea nitrogen, renal pathology, and chemokine expression and dramatically reduced the induction of inducible
nitric oxide synthase and
caspase-3 activation in the kidney
Xing et al., J Huazhong Univ Sci Technolog Med Sci 2006
:
Consequently, the mechanisms of rosuvastatin 's neural protection on ischemic brain injury are to enhance expression of
eNOS , to
inhibit expression of iNOS and activated
caspase-3
Braun et al., Int J Neurosci 2009
(Disease Models, Animal...) :
Inducible
nitric oxide synthase mediates hippocampal
caspase-3 activation in pneumococcal meningitis
Monti et al., J Mol Cell Cardiol 2010
:
We demonstrate here that serum deprivation of CVEC increased
eNOS mediated ROS levels, activated
caspase-3 , reduced Akt phosphorylation and cell number
D'Agostino et al., Biol Psychiatry 2012
(Alzheimer Disease...) :
According with the neuroprotective profile of PEA observed during behavioral studies, experimental molecular and biochemical markers induced by Ab25-35 injection, such as lipid peroxidation, protein nytrosylation, inducible
nitric oxide synthase induction , and
caspase3 activation, were reduced by PEA treatment
Wang et al., Brain Res Bull 2012
(Hypoxia-Ischemia, Brain) :
In the meanwhile, the microbubbles attenuated the production of inducible
nitric oxide synthase , nitric oxide and tumor necrosis factor-alpha, as well as the
activation of
caspase-3 in insulted side of brain in neonatal rats