Gene interactions and pathways from curated databases and text-mining

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IRF8 — NF1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Huang et al., Mol Cell Biol 2006 (Leukemia, Myeloid) : In the studies presented here, we determine that ICSBP tyrosine phosphorylation is necessary for the activation of NF1 transcription ... Activated SHP2-PTP mutants thereby inhibit ICSBP dependent NF1 transcription, impairing this negative feedback mechanism on cytokine activated Ras
Koenigsmann et al., Blood 2009 (Leukemia...) : Transcription of NF1 is directly controlled by ICSBP