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CD40LG — ICAM1

Text-mined interactions from Literome

von Leoprechting et al., Cancer Res 1999 (Melanoma) : CD40 ligation on MM by CD40L transfected murine L-cells or by a soluble CD40L fusion protein up-regulated their expression of intercellular adhesion molecule-1 and MHC class I and class II molecules and their secretion of IL-6, IL-8, tumor necrosis factor-a, and granulocyte macrophage colony stimulating factor and also induced a rapid activation of the transcription factor nuclear factor kappaB
Kuroiwa et al., J Immunol 1999 (Glomerulonephritis) : Human peripheral blood monocytes, primed with IFN-gamma and GM-CSF, were activated with CD40 ligand (CD40L) or TNF-alpha and cocultured with MC. CD40L activated monocytes induced higher levels of IL-6, monocyte chemoattractant protein-1 ( MCP-1 ) and ICAM-1 synthesis by MC. Separation of CD40L activated monocytes from MC by a porous membrane decreased the mesangial synthesis of IL-6 by 80 % and ICAM-1 by 45 %, but had no effect on MCP-1
Evans et al., J Immunol 2000 : Induction of B7-1 ( CD80 ) and increased or sustained expression of CD44H, ICAM-1 ( CD54 ), and B7-2 ( CD86 ) are dependent on the interaction of CD40 ligand with CD40 ... Induction of B7-1 ( CD80 ) and increased or sustained expression of CD44H, ICAM-1 ( CD54 ), and B7-2 ( CD86 ) are dependent on the interaction of CD40 ligand with CD40
Haswell et al., Eur J Immunol 2001 : Moreover, stimulation with dodecameric CD154 induced higher levels of the costimulatory molecules ICAM-1 and CD86
Mehl et al., J Immunol 2001 : Its potential usefulness is illustrated by its ability to inhibit the CD40 ligand stimulated increases of HLA and CD54 expression, molecules involved in Ag recognition and lymphocyte recruitment leading to organ rejection
Takahashi et al., J Pharmacol Exp Ther 2003 : Although interleukin (IL)-18 induced the expression of ICAM-1, B7.2, CD40, and CD40L , PGE1 prevented IL-18 induced expression of ICAM-1 , B7.2, and CD40
Saito et al., Mod Rheumatol 2007 (Sjogren's Syndrome) : CD40-CD40 ligand signal induces the intercellular adhesion molecule-1 expression through nuclear factor-kappa B p50 in cultured salivary gland epithelial cells from patients with Sjögren 's syndrome ... First, ICAM-1 expression was determined with reverse transcriptase-polymerase chain reaction and flow cytometry in the presence or absence of soluble CD40L ( sCD40L )
Li et al., American journal of physiology. Renal physiology 2009 (MAP Kinase Signaling System) : IL-8 amplifies CD40/CD154 mediated ICAM-1 production via the CXCR-1 receptor and p38-MAPK pathway in human renal proximal tubule cells ... CD154/CD40 mediated ICAM-1 upregulation was not affected by preincubation of monolayers with the CXCR-1 blocking antibody, indicating that ICAM-1 expression occurs independent of CD154 mediated IL-8 production ... This cascade of events is independent of CD40/CD154 mediated IL-8 stimulation and ICAM-1 production and serves to amplify the inflammatory response
Zhao et al., Invest Ophthalmol Vis Sci 2010 (Graves Ophthalmopathy...) : Inhibition of the ERK1/2, p38, JNK, and NF-kappaB pathways blocked CD40L induced ICAM-1 secretion ... Analyses of ICAM-1 mRNA synthesis revealed that CD40L induced ICAM-1 expression was mediated by multiple factors ... CD40L can potently induce ICAM-1 expression in OF cells through multiple signal pathways ... The p38 MAPKs and NF-kappaB pathways may play an important permissive role in CD40L induced ICAM-1 expression in OFs
Ranheim et al., Cell Immunol 1995 : Tumor necrosis factor-alpha facilitates induction of CD80 ( B7-1 ) and CD54 on human B cells by activated T cells : complex regulation by IL-4, IL-10, and CD40L
Yellin et al., J Leukoc Biol 1995 (Arthritis, Rheumatoid...) : CD40 expression on fibroblasts is functionally significant because CD40L-CD40 interactions induce SM fibroblast CD54 ( intercellular adhesion molecule-1 ) and CD106 ( vascular cell adhesion molecule-1 ) up-regulation
Ludewig et al., Eur J Immunol 1995 : Furthermore, IL-10 led to the down-regulation of various surface antigens, especially of CD86 and CD54, whereas TNF-alpha and TRAP enhanced the expression of MHC class I and II antigens and of the accessory molecules CD40, CD54 , CD80 and CD86
Gruss et al., Leukemia 1996 (Hodgkin Disease) : The CD30 ligand and CD40 ligand regulate CD54 surface expression and release of its soluble form by cultured Hodgkin and Reed-Sternberg cells
Wooldridge et al., Cancer Immunol Immunother 1997 (Lymphoma, B-Cell) : Expression of CD80, CD86, and ICAM-1 on lymphoma cells was up-regulated by soluble CD40 ligand