Gene interactions and pathways from curated databases and text-mining

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IL1B — PARP1

Text-mined interactions from Literome

Sharp et al., Inflammation 2001 (Inflammation) : PARP inhibition with GPI 6150 blocked the IL-1beta mediated stimulation of both ICAM-1 and E-selectin expression, and blocked TNF-alpha stimulation of ICAM-1 expression at 24 h
GarcĂ­a et al., Arthritis Res Ther 2006 (Arthritis, Experimental...) : Interestingly, quantitative real-time PCR and ELISA analysis revealed that the absence of PARP-1 down-regulated IL-1beta and monocyte chemotactic protein 1 expression in arthritic joints whereas tumor necrosis factor-alpha transcription was not impaired
Shakibaei et al., Ann N Y Acad Sci 2007 : Resveratrol inhibits IL-1 beta induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro
Huang et al., Biochem Biophys Res Commun 2009 (Disease Models, Animal...) : Minocycline repressed the expression of TNF-alpha, IL-1beta , and iNOS, decreased the apoptotic index, and inhibited poly(ADP-ribose) polymerase-1 ( PARP-1 ) activity in the mouse small intestine