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GAPDH — MAPK13
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
de la Monte et al., Alcohol Clin Exp Res 1999
:
This study explores the roles of the Grb2- and Syp binding motifs of IRS-1 in relation to the inhibitory effects of ethanol on insulin stimulated DNA synthesis, proliferating cell nuclear antigen ( PCNA ) and
glyceraldehyde 3-phosphate dehydrogenase ( GAPDH ) expression, and
activation of
mitogen activated protein kinase ( MAPK ), which is known to be essential for cell proliferation
Mookherjee et al., J Immunol 2009
:
Consistent with that, this study demonstrated the importance of the GAPDH interactions with these peptides since gene silencing of
GAPDH resulted in impaired p38
MAPK signaling, downstream chemokine and cytokine transcriptional responses induced by LL-37 and IDR-1, and LL-37 induced cytokine production