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PARP1 — SELP
Text-mined interactions from Literome
Hassa et al., J Biol Chem 2001
:
Finally, we showed that
PARP-1 is
activating the natural inducible nitric-oxide synthase and
P-selectin promoter in a kappa B-dependent manner upon stimulation of the cells with inflammatory stimuli or cotransfection of p65
Cuzzocrea et al., Biochem Pharmacol 2002
(Disease Models, Animal...) :
The potent
PARP inhibitor 5-aminoisoquinolinone ( 5-AIQ ) reduced the degree of lung injury and
attenuated the expression of
P-selectin and ICAM-1 as well as the recruitment of neutrophils into the injured lung
Cuzzocrea et al., Shock 2004
(Reperfusion Injury...) :
Administration of WY 14643 also markedly reduced the nitrotyrosine formation, poly ( adenosine diphosphate [ ADP ] -ribose ) polymerase (
PARP )
activation , up-regulation of ICAM-1, and expression of
P-selectin during reperfusion