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CHUK — FOXO3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind_translation Interaction:
CHUK
—
FOXO3
(affinity chromatography technology)
Hu et al., Cell 2004*
-
IRef Bind_translation Interaction:
CHUK
—
FOXO3
(experimental interaction detection)
Hu et al., Cell 2004*
-
IRef Bind_translation Interaction:
CHUK
—
FOXO3
(coimmunoprecipitation)
Hu et al., Cell 2004*
-
IRef Biogrid Interaction:
CHUK
—
FOXO3
(direct interaction, pull down)
Hu et al., Cell 2004*
-
IRef Biogrid Interaction:
CHUK
—
FOXO3
(physical association, affinity chromatography technology)
Hu et al., Cell 2004*
-
IRef Hprd Interaction:
CHUK
—
FOXO3
(in vitro)
Hu et al., Cell 2004*
-
IRef Hprd Interaction:
CHUK
—
FOXO3
(in vivo)
Hu et al., Cell 2004*
-
IRef Innatedb Interaction:
CHUK
—
FOXO3
(unknown, -)
Hu et al., Cell 2004*
-
IRef Ophid Interaction:
CHUK
—
FOXO3
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Hu et al., Cell 2004
(Breast Neoplasms...) :
We provide evidence for such a mechanism by showing that
IkappaB kinase (IKK) physically interacts with, phosphorylates, and
inhibits FOXO3a independent of Akt and causes proteolysis of FOXO3a via the Ub-dependent proteasome pathway
Lesniewski et al., J Gerontol A Biol Sci Med Sci 2011
:
We hypothesized that
I kappa B kinase (IKK) mediated nuclear factor kappa B and
forkhead BoxO3a phosphorylation will be associated with age related endothelial dysfunction