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Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of GAB1-PIK3R2
(decreases)
Evidence: In the parentalHCC827 cell line, two major phosphotyrosine proteins, ERBB3 (~240 KD) and growth-factor-receptor bound protein 2 (Grb2) associated binder 1 (Gab1) (~120 KD), a known PI3K adaptor protein (14), coprecipitated with p85 (Fig. 2C), and both interactions were disrupted by gefitinib alone.