Gene interactions and pathways from curated databases and text-mining

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CAMP — VDR

Pathways - manually collected, often from reviews:

  • KEGG Tuberculosis: VDR → CAMP (protein-protein, activation)

Text-mined interactions from Literome

Chun et al., PloS one 2012 : The predicted induction of CAMP in vivo was minimal at basal settings but increased with enhanced expression of VDR ( 5-fold ) and CYP27B1 ( 10-fold )
Dixon et al., BMC research notes 2012 : Transcription of the cathelicidin antimicrobial peptide ( CAMP ) gene is induced by binding of the bioactive form of vitamin D, 1,25-dihydroxyvitamin D, to the vitamin D receptor