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JUN — SPARC

Text-mined interactions from Literome

van Dam et al., Oncogene 2001 (Cell Transformation, Neoplastic...) : Repression of the matrix component SPARC by Jun is essential for the induction of fibrosarcomas
Briggs et al., Oncogene 2002 (Breast Neoplasms...) : We previously demonstrated that expression of the SPARC/osteonectin gene, while undetectable in the MCF7 cell line, is highly induced in response to stable c-Jun overexpression ( c-Jun/MCF7 ) ... These results demonstrate that SPARC plays an important role in stimulating motility and the invasive behavior of c-Jun/MCF7 cells and that SPARC promoter activation by c-Jun appears to occur through an indirect mechanism