Gene interactions and pathways from curated databases and text-mining

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JUN — PAK2

Text-mined interactions from Literome

Chen et al., J Exp Med 1999 : Transient expression of a kinase-defective PAK blocked both S. typhimurium- and SopE induced c-Jun NH2-terminal kinase (JNK) activation but did not interfere with bacteria induced actin cytoskeleton rearrangements
Chan et al., J Cell Biochem 2007 : We further show that MG-induced apoptosis of osteoblasts involves specific apoptotic biochemical changes, including oxidative stress, c-Jun N-terminal kinase (JNK) activation , mitochondrial membrane potential changes, cytochrome C release, increased Bax/Bcl-2 protein ratios, and activation of caspases ( caspase-9, caspase-3 ) and p21 activated protein kinase 2 (PAK2)