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ANGPT2 — FLT1

Pathways - manually collected, often from reviews:

• WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: EFNA1/FGF1/FGF11/FGF10/EFNA2/EGF/FGF12/CSF1/ANGPT4/ANGPT2/ANGPT1/VEGFA/EFNA3/EFNA4/EFNA5/FGF14/FGF19/FGF17/FGF18/FGF2/FGF3/FGF4/FGF6/FGF7/FGF8/FGF9/FIGF/HGF/IGF1/INS/INS/KITLG/VEGFC/VEGFB/PDGFB/PGF/PDGFA/NGF/PDGFC/FGF21/FGF22/PDGFD/FGF20/FGF16 → FGFR2/KDR/INSR/FGFR3/IGF1R/KIT/FGFR1/EPHA2/EGFR/CSF1R/FGFR4/FLT1/FLT4/NGFR/MET/PDGFRA/PDGFRB/TEK (activation)
  

Text-mined interactions from Literome

Wulff et al., J Clin Endocrinol Metab 2001 : Luteal Flt mRNA expression is dependent upon VEGF, and VEGF inhibition results in abortive increases in expression of VEGF, angiopoietin-2 , and Tie-2
Takazawa et al., Kidney Int 2005 (Glomerulonephritis...) : At the early stage ( day 6 ), glomerular expression of VEGF and receptors flk-1 and flt-1 as well as Ang-1, and receptor Tie2 were increased, and glomerular monocyte infiltration and the expression of angiopoietin-2 (Ang-2) , a natural antagonist of Ang-1, were reduced
Kitayama et al., Am J Hypertens 2006 (Disease Models, Animal...) : The increase of flk-1 and flt-1 ( VEGF receptors ) and tie-2 ( Ang1 receptor ) induced by ang II was significantly suppressed by PD123319