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CD3E — NFKB1
Text-mined interactions from Literome
Tsuji-Takayama et al., Cell Immunol 1999
:
We conclude that dual signaling consisting of IL-18 induced
NF-kappaB activation and
TCR/CD3 mediated NFAT
activation is crucial for IFN-gamma production by IL-18 in murine Th1 cells
Pimentel-Muiños et al., Eur J Immunol 1995
:
The
regulation of
nuclear factor (NF)-kappa B activation by the
T cell receptor (TcR)/CD3 complex in primary human T cells has been studied at various times after activation ... These results indicate that the
regulation of
NF-kappa B activation during T cell activation by
TcR/CD3 signals is biphasic : TcR/CD3 triggers its immediate translocation, which is transient if no TNF-alpha is present
Pimentel-Muiños et al., J Immunol 1994
:
Cyclosporin A, which prevented lymphokine mRNA transcription, inhibited more than 90 % of the IL-2R alpha and
NF-kappa B levels
induced by
TCR/CD3 mediated activation
Gringhuis et al., Blood 1997
(Leukemia-Lymphoma, Adult T-Cell) :
T-cell receptor (TCR)/CD3 engagement
results in the activation of nuclear factor of activated T cells ( NFAT ), activator protein-1 (AP-1), and
nuclear factor kappaB (NFkappaB) , whereas the CD28 responsive complex (CD28RC) is activated in response to the CD28 signal