Gene interactions and pathways from curated databases and text-mining

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IL2 — PGF

Text-mined interactions from Literome

Leung et al., J Endocrinol 2001 : In contrast, when endometrium was collected in early luteolysis, none of the interleukins altered OTR expression or caused a significant stimulation of PGF ( 2alpha ) production but IL-2 increased PGE ( 2 ) ... IL-I and -2 and LPS are therefore unlikely to initiate luteolysis but may cause raised production of PGF ( 2alpha ) during uterine infection
Li et al., J Clin Endocrinol Metab 2001 : Interleukin-2 (IL-2) and IL-15 up-regulated VEGF-C, but not PlGF or Ang2, mRNA levels in isolated NK cells
Franczak et al., Theriogenology 2012 : We studied the effect of tumor necrosis factor a (TNFa), interleukin 1ß (IL1ß) and interleukin 6 (IL6) on : 1 ) endometrial release of prostaglandin F2a (PGF2a) , 2 ) expression of the terminal enzyme of PGF2a synthesis -- PGF synthase mRNA (PGFS mRNA), 3 ) secretion of PGF ( 2 ) a metabolite -- 13,14-dihydro-15-keto PGF2a ( PGFM ) by the endometrium and 4 ) presence and activity of endometrial NAD dependent 15-hydroxyprostaglandin dehydrogenase ( 15-PGDH )