Pan et al., Cell Mol Immunol 2004
(Drug-Induced Liver Injury) :
Western blot analyses show that overexpression of IL-22 significantly enhances activation of STAT3 and expression of Bcl-xL , Bcl-2, and Mcl-1 proteins in liver injury induced by Con A
Nakayamada et al., Immunity 2011
:
Herein, we showed interleukin-12 acting via the transcription factor STAT4 induced both Il21 and Bcl6 genes, generating cells with features of both Tfh and Th1 cells