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IFI44 — INS

Text-mined interactions from Literome

Conejo et al., J Cell Physiol 2001 : Insulin ( 50 nM ) rapidly ( 5 min ) stimulated beta-chain insulin receptor, activated the phosphatidylinositol (PI) 3-kinase/Akt/p70S6-kinase signaling pathway, as well as phosphorylated both p44/p42- and p38-mitogen activated protein kinases ( MAPKs )
Massao Hirabara et al., FEBS Lett 2003 : Palmitate reduced insulin stimulated phosphorylation of insulin receptor substrate-1/2, Akt, and p44/42 mitogen activated protein kinases
Kralisch et al., Mol Cell Endocrinol 2005 : Moreover, p44/42 mitogen activated protein kinase appears to partly mediate the negative effect of insulin but not TNFalpha on ATGL
Wada et al., Endocrinology 2007 : Interestingly, long-term ( 48-h ) pretreatment with nicotine increased the amount of alpha7-AChR in the plasma membrane and insulin induced phosphorylation of p44/42-MAPK ... These results provide the first evidence that acute exposure to nicotine enhances insulin induced mitogenesis predominantly by affecting the phosphorylation of p44/42-MAPK and that chronic exposure further augments the insulin signal via up-regulation of alpha7-nAChR, which may be crucial for the development and progression of atherosclerosis in large vessels
Harwood et al., J Biol Chem 2008 (MAP Kinase Signaling System) : The effect of rapamycin on IGF-I or insulin activation of p44/42 was recapitulated by amino acid deprivation
Chenal et al., Eur J Neurosci 2008 : Investigation of the putative signalling pathways leading to translation activation revealed that insulin and IGF-1 induced p44- and p42 MAPK, Akt and mTOR phosphorylation
Sharma et al., Mol Cell Biol 1997 : In both cell types, overexpression of either the PTB or the SAIN protein caused a significant decrease in insulin induced tyrosine phosphorylation of IRS-1 and Shc proteins, IRS-1 associated phosphatidylinositol 3-kinase (PI 3-K) enzymatic activity, p70s6k activation, and p44 and p42 mitogen activated protein kinase ( MAPK ) phosphorylation