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IL8 — WNT4
Text-mined interactions from Literome
Masckauchán et al., Angiogenesis 2005
:
Wnt/beta-catenin signaling
induces proliferation, survival and
interleukin-8 in human endothelial cells
Heijink et al., Thorax 2013
(Pulmonary Disease, Chronic Obstructive) :
Exogenously added
WNT-4 significantly
increased CXCL8/IL-8 , IL-6, CCL5/RANTES, CCL2/MCP-1 and vascular endothelial growth factor ( VEGF ) secretion in 16HBE, but did not affect the canonical WNT target genes MMP-2, MMP-9, fibronectin, ß-catenin, Dickkopf and axin-2, and induced activation of the non-canonical signalling molecule p38 ... Moreover,
WNT-4 potentiated the CSE induced upregulation of
IL-8 and VEGF