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ANG — CTGF
Text-mined interactions from Literome
de las Heras et al., J Renin Angiotensin Aldosterone Syst 2006
(Body Weight...) :
We have evaluated the
role of
connective tissue growth factor (CTGF) in vascular and renal damage associated with hypertension and possible interactions with
angiotensin II (Ang II)
Tsutsui et al., Hypertens Res 2007
(Body Weight...) :
Moreover, candesartan directly inhibited
Ang II-mediated
induction of
CTGF in cultured cardiac fibroblasts
Tung et al., Toxicol In Vitro 2010
:
Angiotensin (ANG) II may
induce CTGF expression in the heart and kidney and plays an important role in the pathogenesis of lung fibrosis
Ren et al., American journal of physiology. Renal physiology 2012
:
Angiotensin II (ANG II) in the CNT lumen
enhances CTGF via PKC
Li et al., Zhonghua Gan Zang Bing Za Zhi 2012
:
Ang ( 1-7 )
inhibited the Ang II-stimulated up-regulation of RhoA, ROCK, and
CTGF ...
Ang ( 1-7 ) can
inhibit the Ang II-stimulated up-regulation of RhoA, ROCK and
CTGF in hepatic stellate cells, indicating that the ACE2-Ang ( 1-7 ) -Mas axis, an important branch of the renin-Ang-aldosterone system is involved in the occurrence and development of liver fibrosis
Wei et al., J Cell Physiol 2013
(Fibrosis...) :
Here, we show that inhibition of NF-?B in cardiac fibroblast restores miR-26a expression, attenuating collagen I, and
CTGF gene expression in the
presence of
Ang II, conferring a feedback regulatory mechanism in cardiac fibrosis