Boyle et al., Curr Biol 2007
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We provide evidence that Abl/Arg mediated phosphorylation of cortactin is required for this PDGF induced dorsal-wave response
Dudek et al., Mol Biol Cell 2010
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Conversely, reduced c-Abl expression in EC ( siRNA ) markedly attenuated S1P mediated cortical actin formation, reduced the EC modulus of elasticity ( assessed by atomic force microscopy ), reduced nmMLCK and cortactin tyrosine phosphorylation, and attenuated S1P mediated barrier enhancement