Gene interactions and pathways from curated databases and text-mining

◀ Back to IRS2

IRS2 — ZGLP1

Text-mined interactions from Literome

Dalle et al., Cell Signal 2011 (Diabetes Mellitus) : Importantly, recent studies found that ß-arrestin-1 mediates GLP-1 signalling to insulin secretion, GLP-1 antiapoptotic effect by phosphorylating the proapoptotic protein Bad through ERK1/2 activation, and PACAP potentiation of glucose induced long lasting ERK1/2 activation controlling IRS-2 expression
Wang et al., Metabolism 2011 : The effects of GLP-1 and/or candesartan on glucolipotoxicity induced apoptosis and the phosphorylation of insulin receptor substrate-2 (IRS-2) , protein kinase B (PKB), and forkhead box O1 (FoxO1) were evaluated by using MIN6 cells and isolated mouse pancreatic islets