◀ Back to MAP3K7
MAP2K3 — MAP3K7
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
MAP2K3
→
MAP3K7
(increases, MAP3K7 Activity, MAP2K3 Activity)
Evidence: exercise leads to the activation of at least three MAPK signalling pathways, i.e. ERK1/2, p38 MAPK and JNK, in skeletal muscle (Zierath, 2002).
-
BioCarta nfkb activation by nontypeable hemophilus influenzae:
TAK1 (MAP3K7)
→
MEK3 (MAP2K3)
(modification, activates)
-
BioCarta mapkinase signaling pathway:
ASK1/TAK1/MAP3K11 (MAP3K5/MAP3K11/MAP3K7)
→
MEK3/MEK6 (MAP2K3/MAP2K6)
(modification, activates)
-
KEGG MAPK signaling pathway:
MAP3K7
→
MAP2K3
(protein-protein, phosphorylation)
-
KEGG Toxoplasmosis:
MAP3K7
→
MAP2K3/MAP2K6
(protein-protein, activation)
-
Reactome Reaction:
MAP2K3
→
MAP3K7
(reaction)
Thiefes et al., J Biol Chem 2005, Sato et al., Nat Immunol 2005, Yamaguchi et al., Science 1995, Raingeaud et al., Mol Cell Biol 1996
-
WikiPathways Regulation of toll-like receptor signaling pathway:
MAP3K7
→
MAP2K3/MAP2K6
(activation)
-
WikiPathways Toll-like Receptor Signaling Pathway:
MAP3K7
→
MAP2K3/MAP2K6
(activation)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tu et al., Cell Signal 2003
:
They consist of a three-kinase module in which a mitogen activated protein kinase kinase kinase (
MAP3K )
activates a
mitogen activated protein kinase kinase ( MAP2K ), which in turn activates MAPK
Huang et al., Biochem Biophys Res Commun 2003
:
MAP3Ks are components of a three tiered protein kinase pathway in which a
MAP3K phosphorylates and
activates a
mitogen activated protein kinase kinase ( MAP2K ), which in turn activates a mitogen activated protein kinase ( MAPK )